Polynucleotides are purified DNA fragments extracted from trout or salmon that work by:

• Stimulating collagen production

• Improving skin elasticity

• Supporting tissue repair

• Reducing inflammation

• Enhancing skin quality at a cellular level

They are often described as a regenerative treatment, rather than a volumising one.

• Fine lines and early skin ageing

• Crepey or thinning skin

• Under-eye skin quality

• Loss of elasticity

• Dull or tired-looking skin

• Skin that feels fragile or weakened

They are particularly effective in delicate areas where volume isn’t appropriate.

Polynucleotides are often part of a broader skin strategy, rather than a standalone trend treatment.

Polynucleotides work gradually.

You may notice:

• Improved skin texture

• Increased elasticity

• Healthier, more resilient skin

• Reduction in fine crepey lines

• Brighter under-eye appearance

Most patients require a course of treatments, with improvements developing over several weeks.

Usually a course of 3-4 is recommended spaced 2 weeks apart, followed by maintenance every 6-9 months.

Polynucleotides are generally considered very safe, biocompatible and well-tolerated for skin rejuvenation they have a long history of medical use for wound healing.

Polynucleotides may be ideal if you:

• Want natural skin improvement without volume

• Prefer regenerative treatments

• Are concerned about under-eye skin quality

• Want to improve skin strength and elasticity

• Value subtle, long-term results

They are often chosen by patients who want to look healthier and fresher, not treated.

Polynucleotides may not be appropriate if:

• You are seeking immediate volumising results

• Your concerns are primarily structural (where filler or Radiesse may be more appropriate)

• You are pregnant or breastfeeding

• You have certain medical conditions (assessed at consultation)

If it’s not the right option, I will always explain why and suggest alternatives.

Discomfort is usually mild. A numbing cream can be applied if appropriate.

Most patients tolerate the treatment well.

Downtime is usually minimal.

You may experience:

• Mild swelling

• Small injection marks

• Occasional bruising

Most patients return to normal activities within 24–48 hours.

Aftercare advice is provided to support healing.

Your consultation is thorough and honest.

We will:

• Assess your skin quality and concerns

• Discuss your goals

• Decide if polynucleotides are appropriate

• Talk through expected results and treatment course

• Create a personalised plan